BDBM50099859 CHEMBL29220::Sodium; (E)-2-amino-5-(2-fluoro-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoate

SMILES CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccccc1F

InChI Key InChIKey=AATKXXQGCCDEFN-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099859   

TargetSodium- and chloride-dependent glycine transporter 2(Rat)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099859(Sodium; (E)-2-amino-5-(2-fluoro-phenyl)-5-(4-isopr...)
Affinity DataIC50: 290nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099859(Sodium; (E)-2-amino-5-(2-fluoro-phenyl)-5-(4-isopr...)
Affinity DataIC50: 8.02E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed