BDBM50099980 6,7-Dimethoxy-4-(4-methylsulfanyl-phenylamino)-quinoline-3-carbonitrile::CHEMBL30597

SMILES COc1cc2ncc(C#N)c(Nc3ccc(SC)cc3)c2cc1OC

InChI Key InChIKey=DRHDIJVDQNOQEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099980   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099980(6,7-Dimethoxy-4-(4-methylsulfanyl-phenylamino)-qui...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using coupled MEK assay (which uses activated Raf to activate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099980(6,7-Dimethoxy-4-(4-methylsulfanyl-phenylamino)-qui...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase in coupled activated Raf/MEK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed