BDBM50099984 4-(4-Furan-3-ylmethyl-phenylamino)-6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinoline-3-carbonitrile::CHEMBL30790
SMILES COc1cc2c(Nc3ccc(Cc4ccoc4)cc3)c(cnc2cc1OCCCN1CCOCC1)C#N
InChI Key InChIKey=XZEXYZLBZDJFEC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50099984
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using coupled MEK assay (which uses activated Raf to activate an...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using direct MEK assay (which by-passes the need for activated R...More data for this Ligand-Target Pair