BDBM50100708 5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridine-2-sulfonic acid trifluoromethyl ester::CHEMBL300837

SMILES FC(F)(F)OS(=O)(=O)c1ccc(cn1)C1CC2CCC1N2

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100708   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100708(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridine-2-sulfo...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100708(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridine-2-sulfo...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100708(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridine-2-sulfo...)
Affinity DataKi: >10nMAssay Description:Binding affinity towards rat alpha2-beta2 neuronal nAChR expressed in Xenopus oocytes using [3H]epibatidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed