BDBM50100891 2-Phenyl-1H-benzoimidazole-5-carboxamidine::2-Phenyl-3H-benzoimidazole-5-carboxamidine::CHEMBL96917

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1

InChI Key InChIKey=YOGKYTKBSDBMTL-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50100891   

TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  5.50E+4nMAssay Description:Compound was tested against Human Serine Protease TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  5.50E+4nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  1.25E+5nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  3.50E+5nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  3.81E+5nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSporulation kinase A(Bacillus subtilis (strain 168))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-3H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2018
Entry Details Article
PubMed