BDBM50101019 1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydro-1-pyrazinylcarbonyloxy}-5-[4-(2-hexahydro-4-pyridinylethylcarbamoyl)hexahydro-1-pyrazinylcarbonyloxy]cyclooctane::CHEMBL40491

SMILES NC(=N)c1ccc(CNC(=O)N2CCN(CC2)C(=O)O[C@@H]2CCC[C@@H](CCC2)OC(=O)N2CCN(CC2)C(=O)NCCC2CCNCC2)cc1

InChI Key InChIKey=HMISKNUPRCAHAW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101019   

TargetTryptase beta-2/delta/gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101019(1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydr...)
Affinity DataKi:  0.910nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101019(1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydr...)
Affinity DataKi:  4.72E+4nMAssay Description:Inhibition of trypsin in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101019(1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydr...)
Affinity DataKi:  1.11E+5nMAssay Description:Inhibition of thrombin in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101019(1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydr...)
Affinity DataKi:  2.87E+5nMAssay Description:Inhibition plasmin in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed