BDBM50101523 (R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-p-tolyl-hexanoic acid::3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-p-tolyl-hexanoic acid::CHEMBL78335

SMILES Cc1ccc(CCC[C@H](CC(O)=O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=OUOSIGGTYBFYMF-IAPPQJPRSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50101523   

Target72 kDa type IV collagenase(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  384nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  384nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  4.78E+4nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  4.78E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101523((R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-...)
Affinity DataKi:  4.79E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed