BDBM50101525 (R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-hexanoic acid::6-(4-Chloro-phenyl)-3-{2-cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-hexanoic acid::CHEMBL420376

SMILES NS(=O)(=O)c1ccc(CCNC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CCCc2ccc(Cl)cc2)CC(O)=O)cc1

InChI Key InChIKey=LMZDADMPZWYRMS-SQHAQQRYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50101525   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  1nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  1.03nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  358nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  358nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50101525((R)-6-(4-Chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article