BDBM50101725 CHEMBL300771::[4-(Acetyl-benzyl-amino)-cyclohexyl]-((S)-4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid

SMILES COc1ccc(-c2ccc(S(=O)(=O)N[C@@H](C(=O)O)C3CCC(N(Cc4ccccc4)C(C)=O)CC3)cc2)cc1

InChI Key InChIKey=BTZXQMHZPVTFBL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101725   

Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101725BDBM50101725([4-(Acetyl-benzyl-amino)-cyclohexyl]-((S)-4'-metho...)
Affinity DataIC50: 0.600nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101725BDBM50101725([4-(Acetyl-benzyl-amino)-cyclohexyl]-((S)-4'-metho...)
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101725BDBM50101725([4-(Acetyl-benzyl-amino)-cyclohexyl]-((S)-4'-metho...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101725BDBM50101725([4-(Acetyl-benzyl-amino)-cyclohexyl]-((S)-4'-metho...)
Affinity DataIC50: 284nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101725BDBM50101725([4-(Acetyl-benzyl-amino)-cyclohexyl]-((S)-4'-metho...)
Affinity DataIC50: 845nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed