BDBM50101729 ((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-oxo-imidazolidin-1-yl)-cyclohexyl]-acetic acid::CHEMBL293411

SMILES COc1ccc(-c2ccc(S(=O)(=O)N[C@@H](C(=O)O)C3CCC(N4CCNC4=O)CC3)cc2)cc1

InChI Key InChIKey=XXCBSIYZQACPFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101729   

Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101729BDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101729BDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101729BDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50: 98nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101729BDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50: 3.31E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101729BDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50: 4.79E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed