BDBM50101771 (S)-2-(Propane-1-sulfonylamino)-3-({5-[2-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-ethyl]-thiophene-2-carbonyl}-amino)-propionic acid::CHEMBL59403

SMILES CCCS(=O)(=O)N[C@@H](CNC(=O)c1ccc(CCC(=O)NC2=NCCCN2)s1)C(O)=O

InChI Key InChIKey=DQHQIVAKLNPCRD-ZDUSSCGKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101771   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101771((S)-2-(Propane-1-sulfonylamino)-3-({5-[2-(1,4,5,6-...)
Affinity DataIC50:  22nMAssay Description:Concentration required to reduce binding of human 293 cell attachment to immobilized vitronectin receptor(Vn/293) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101771((S)-2-(Propane-1-sulfonylamino)-3-({5-[2-(1,4,5,6-...)
Affinity DataIC50:  105nMAssay Description:Concentration required to reduce binding of human 293 cell attachment to immobilized vitronectin receptor(Vn/293) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101771((S)-2-(Propane-1-sulfonylamino)-3-({5-[2-(1,4,5,6-...)
Affinity DataIC50:  4nMAssay Description:Concentration required to reduce binding of fibrinogen (Fg) to alpha IIb beta3 integrin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed