BDBM50102087 (6-{2-[Bis-(2-methoxy-ethyl)-amino]-ethoxy}-7-methoxy-quinazolin-4-yl)-(3-chloro-4-fluoro-phenyl)-amine::CHEMBL294395

SMILES COCCN(CCOC)CCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC

InChI Key InChIKey=WFOGDVXKFPKAIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102087   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102087((6-{2-[Bis-(2-methoxy-ethyl)-amino]-ethoxy}-7-meth...)
Affinity DataIC50:  61nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed