BDBM50102210 5-Dimethylamino-naphthalene-1-sulfonic acid [4-guanidino-1-(piperidine-1-carbonyl)-butyl]-amide; hydrochloride::CHEMBL170488::CHEMBL545680

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCCC1

InChI Key InChIKey=WMTAGTJIKZZYPR-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102210   

TargetProthrombin(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50102210(CHEMBL170488 | CHEMBL545680 | 5-Dimethylamino-naph...)
Affinity DataKi:  83nMAssay Description:Binding affinity determined against thrombin by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50102210(CHEMBL170488 | CHEMBL545680 | 5-Dimethylamino-naph...)
Affinity DataKi:  2.34E+3nMAssay Description:Binding affinity determined against trypsin by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50102210(CHEMBL170488 | CHEMBL545680 | 5-Dimethylamino-naph...)
Affinity DataIC50: 1.00E+9nMAssay Description:Bovine thrombin concentration at which clotting time was prolonged 2x over the control.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed