BDBM50102479 4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid 2-methoxy-ethyl ester::CHEMBL311004

SMILES COCCOC(=O)N1CCC(CC1)C(NS(=O)(=O)c1ccc(cc1)-c1ccc(SC)cc1)C(O)=O

InChI Key InChIKey=FNURWSLLBXZLRC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50102479   

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  40.6nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  7.30nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102479(4-[Carboxy-(4'-methylsulfanyl-biphenyl-4-sulfonyla...)
Affinity DataIC50:  1.08E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed