BDBM50102480 2-(1-((2-methoxyethoxy)carbonyl)piperidin-4-yl)-2-(4-phenoxyphenylsulfonamido)acetic acid::4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl]-piperidine-1-carboxylic acid 2-methoxy-ethyl ester::CHEMBL82113

SMILES COCCOC(=O)N1CCC(CC1)C(NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(O)=O

InChI Key InChIKey=PYGZWPVJQNBFNS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50102480   

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 25.8nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 58.1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 141nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 399nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 597nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102480(4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed