BDBM50102568 6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL89208

SMILES COC(=O)C1C(c2ccccc2)CC2[C@@H](O)CC1N2C

InChI Key InChIKey=LIYDQJCDMBBSPX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102568   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102568BDBM50102568(6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102568BDBM50102568(6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102568BDBM50102568(6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102568BDBM50102568(6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102568BDBM50102568(6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102568BDBM50102568(6-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed