BDBM50103033 (S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2-methyl-benzyl)-3-pyrrolidin-1-ylmethyl-1H-indol-6-yl]-ureido}-propionylamino)-5-guanidino-pentanoic acid benzylamide::CHEMBL66585

SMILES Cc1ccccc1Cn1cc(CN2CCCC2)c2ccc(NC(=O)N[C@@H](Cc3ccc(cc3)C#N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCc3ccccc3)cc12

InChI Key InChIKey=XKIVAVYUZHQHHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103033   

TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103033((S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2-methyl-be...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103033((S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2-methyl-be...)
Affinity DataIC50: 620nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103033((S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2-methyl-be...)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro displacement of [3H]S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 uM) from thrombin receptor (PAR-1) on the membranes of CHRF-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed