BDBM50103326 (S)-4-((5-(((1-benzyl-2-oxopyrrolidin-3-yl)(butyl)amino)methyl)-1H-imidazol-1-yl)methyl)benzonitrile::4-(5-{[(1-Benzyl-2-oxo-pyrrolidin-3-yl)-butyl-amino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL100415
SMILES CCCCN(Cc1cncn1Cc1ccc(cc1)C#N)[C@H]1CCN(Cc2ccccc2)C1=O
InChI Key InChIKey=AAXGNXOJOSOUQQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50103326
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Concentration required to displace 50% of a potent radiolabeled FTI from farnesyl transferase in cultured H-ras-transformed Rat1 cellsMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of farnesyl transferase using purified recombinant human enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
