BDBM50103414 1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL101848

SMILES CC1(NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1)C1CCCCC1

InChI Key InChIKey=VOSXUKXXGOUBDV-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50103414   

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-5) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  5.40nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed