BDBM50103644 CHEMBL3337623

SMILES Cc1cc2nc(Nc3nc(=O)c(C)c(C)[nH]3)nc(C)c2cc1C

InChI Key InChIKey=RSRFPGRMZHUKON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103644   

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50103644(CHEMBL3337623)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of IL-6-induced STAT3 phosphorylation in human Cal33 cells assessed as nuclear translocation by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50103644(CHEMBL3337623)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT1 phosphorylation in human Cal33 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed