BDBM50103892 CHEMBL3343981

SMILES COc1ccc2nccc(NCCCCCCCNc3ccnc4ccc(OC)cc34)c2c1

InChI Key InChIKey=PXQYFYKYPSFRJV-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50103892   

TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  148nMAssay Description:Binding affinity to human alpha1B adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]-prazosin from human alpha1B adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  316nMAssay Description:Binding affinity to human alpha1A adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]-prazosin from human alpha1A adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  372nMAssay Description:Displacement of [3H]-prazosin from human alpha1D adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  372nMAssay Description:Binding affinity to human alpha1D adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  1.38E+3nMAssay Description:Binding affinity to human 5HT1A receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103892(CHEMBL3343981)
Affinity DataKi:  1.38E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed