BDBM50104377 4-[2-(4-Chloro-phenyl)-5-(2,4-dipropoxy-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL316361

SMILES CCCOc1ccc(-c2[nH]c(nc2-c2ccncc2)-c2ccc(Cl)cc2)c(OCCC)c1

InChI Key InChIKey=ZFXJKZPUDLCSGS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104377   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104377(4-[2-(4-Chloro-phenyl)-5-(2,4-dipropoxy-phenyl)-3H...)
Affinity DataIC50: 13nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104377(4-[2-(4-Chloro-phenyl)-5-(2,4-dipropoxy-phenyl)-3H...)
Affinity DataIC50: 120nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104377(4-[2-(4-Chloro-phenyl)-5-(2,4-dipropoxy-phenyl)-3H...)
Affinity DataIC50: 2.40E+3nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104377(4-[2-(4-Chloro-phenyl)-5-(2,4-dipropoxy-phenyl)-3H...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article