BDBM50104536 (R)-3-(2,6-Dichloro-benzoylamino)-4-(2',6'-dimethoxy-biphenyl-4-yl)-butyric acid::CHEMBL85186

SMILES COc1cccc(OC)c1-c1ccc(C[C@H](CC(O)=O)NC(=O)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=IRBBMKUIRCTMHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104536   

TargetIntegrin alpha-4/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50104536((R)-3-(2,6-Dichloro-benzoylamino)-4-(2',6'-dimetho...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50104536((R)-3-(2,6-Dichloro-benzoylamino)-4-(2',6'-dimetho...)
Affinity DataIC50: 140nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed