BDBM50104997 4-tert-Butyl-N-[6-[2-(5-methylsulfanyl-pyrimidin-2-yloxy)-ethoxy]-5-(4-trifluoromethyl-phenyl)-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL114863

SMILES CSc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)c2-c2ccc(cc2)C(F)(F)F)nc1

InChI Key InChIKey=JWJIPTDWQPLYEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104997   

TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104997(4-tert-Butyl-N-[6-[2-(5-methylsulfanyl-pyrimidin-2...)
Affinity DataIC50:  0.00170nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed