BDBM50105007 CHEMBL177924::N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-4-isopropyl-benzenesulfonamide; compound with methane

SMILES CC(C)c1ccc(cc1)S(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(C)cc1

InChI Key InChIKey=KHOPIGLQZFZWPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105007   

TargetEndothelin-1 receptor(Pig)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105007(CHEMBL177924 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.160nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed