BDBM50105399 (S)-2-{[(S)-2-(3,4-Dimethoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl]-amino}-3-naphthalen-2-yl-propionic acid::CHEMBL91053

SMILES COc1ccc(cc1OC)S(=O)(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(O)=O

InChI Key InChIKey=PMVWESVPNZPORP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105399   

TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105399((S)-2-{[(S)-2-(3,4-Dimethoxy-benzenesulfonyl)-1,2,...)
Affinity DataIC50: 7nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed