BDBM50105464 2,7-Dimethyl-acridine-3,6-diamine::CHEMBL329221

SMILES Cc1cc2cc3cc(C)c(N)cc3nc2cc1N

InChI Key InChIKey=HGHJYCKSBMCGRK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105464   

TargetTelomerase reverse transcriptase(Human)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105464(2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibitory activity against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105464(2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibitory activity against telomerase (Compound released from underivatized resinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105464(2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibitory activity against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105464(2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed