BDBM50106324 CHEMBL3598143

SMILES OC(=O)c1ccc(cc1)-c1nc(C(=O)c2c(Cl)cccc2C(F)(F)F)n2cccnc12

InChI Key InChIKey=QOLJEDPALOAFHA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106324   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL

LigandBDBM50106324(CHEMBL3598143)Copy SMILESCopy InChI

Affinity DataEC50:  84nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2016
Entry Details Article
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TargetPeroxisome proliferator-activated receptor gamma(Human)
Genentech

Curated by ChEMBL

LigandBDBM50106324(CHEMBL3598143)Copy SMILESCopy InChI

Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of fluormone PPARgamma green from GST-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL