BDBM50106862 CHEMBL322890::[1-(3-Benzo[1,3]dioxol-5-ylmethyl-3H-imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-morpholin-4-yl-methanone

SMILES O=C(N1CCOCC1)c1cn(Cc2cncn2Cc2ccc3OCOc3c2)cc1-c1cccc2ccccc12

InChI Key InChIKey=VHSNTJWPNYCXNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106862   

LigandPNGBDBM50106862(CHEMBL322890 | [1-(3-Benzo[1,3]dioxol-5-ylmethyl-3...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of farnesyltransferase activity against H-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106862(CHEMBL322890 | [1-(3-Benzo[1,3]dioxol-5-ylmethyl-3...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106862(CHEMBL322890 | [1-(3-Benzo[1,3]dioxol-5-ylmethyl-3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of farnesyltransferase activity against K-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed