BDBM50107045 CHEMBL421032::N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-N'-(4-methyl-benzoyl)-guanidine

SMILES COc1ccc2[nH]cc(CCN=C(N)NC(=O)c3ccc(C)cc3)c2c1

InChI Key InChIKey=MWVDXILYDYYTKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107045   

TargetSodium channel protein type 2 subunit alpha(Human)
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107045(N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-N'-(4-methyl...)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107045(N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-N'-(4-methyl...)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed