BDBM50107051 CHEMBL108627::N-(4-Methyl-benzoyl)-N'-naphthalen-1-ylmethyl-guanidine

SMILES Cc1ccc(cc1)C(=O)NC(N)=NCc1cccc2ccccc12

InChI Key InChIKey=VPWXWSXUPGZSLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107051   

TargetSodium channel protein type 2 subunit alpha(Human)
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107051(N-(4-Methyl-benzoyl)-N'-naphthalen-1-ylmethyl-guan...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107051(N-(4-Methyl-benzoyl)-N'-naphthalen-1-ylmethyl-guan...)
Affinity DataIC50: 8.85E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed