BDBM50107141 (10-Benzyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl)-acetic acid::CHEMBL342382

SMILES OC(=O)Cn1nc2n(Cc3ccccc3)c3ccccc3n2c(=O)c1=O

InChI Key InChIKey=UYKLQQWWOWXMFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107141   

TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50107141((10-Benzyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50: 360nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50107141((10-Benzyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed