BDBM50107175 1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-phenyl]-acryloyl}-piperidine-4-carboxylic acid::CHEMBL138860

SMILES OC(=O)C1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc3OCCOc3c2)c(Cl)c1

InChI Key InChIKey=ZVEFYLSXTQFRDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107175   

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107175(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50: 145nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(140-150)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed