BDBM50107189 1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-3-nitro-phenyl]-propenone::CHEMBL538164

SMILES CC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc3OCCOc3c2)c(c1)[N+]([O-])=O

InChI Key InChIKey=UAGAHTYBWKROHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107189   

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107189(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benz...)
Affinity DataIC50: 139nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(120-140)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed