BDBM50108212 (S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiazolidine-4-carbonyl]-amino}-3-(2'-methoxy-biphenyl-4-yl)-propionic acid::CHEMBL281550

SMILES COc1ccccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CSCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(O)=O)cc1

InChI Key InChIKey=JHRWRZACLCUNPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108212   

TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108212((S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108212((S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50: 306nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed