BDBM50109443 1-(3,4-Dichloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL349019

SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc(Cl)c(Cl)c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=WRFYJOIKSSTMGJ-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50109443   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 3.05-3.78More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of IB-MECA agonist-mediated cAMP production in CHO cell membranes expressing human Adenosine A3 receptor; range 15-44More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A2B receptor expressed in HEK293 cells; range 91-148More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in HEK293 cells; range 114-179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 324-475More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109443(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-methyl-...)
Affinity DataKi:  3.39E+3nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed