BDBM50109485 CHEMBL163968::N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-phenyl-acetamide::N-(8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-phenylacetamide

SMILES CCCCn1cc2c(n1)nc(NC(=O)Cc1ccccc1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=PKFRXUCKLQZSPD-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50109485   

TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  1.11nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]MRE3008-F20 binding at human Adenosine A3 receptor expressed in HEK cells; range 0.74-1.67More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  1.11nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A2B receptor expressed in HEK293 cells; range 89-116More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in HEK293 cells; range 312-515More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  602nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 525-691More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50109485(N-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed