BDBM50110226 CHEMBL268363::[5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6,9,12,15-pentaoxo-1,4,7,10,13pentaaza-cyclopentadec-2-yl]-acetic acid

SMILES CC1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O

InChI Key InChIKey=SVFSXWWDSXBQLC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50110226   

TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 24nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 662nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed