BDBM50110235 CHEMBL9394::[8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6,9,12,15-pentaoxo-1,2,4,7,10,13hexaaza-cyclopentadec-5-yl]-acetic acid

SMILES CC(C)[C@H]1NC(=O)C(Cc2ccccc2)NC(=O)C(CC(O)=O)NC(=O)NNC(=O)C(CCCNC(N)=N)NC1=O

InChI Key InChIKey=DPVUQQDISRAKFA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50110235   

TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 45nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 530nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed