BDBM50111473 CHEMBL3604937

SMILES CN1CCN(CC1)c1cc(Nc2n[nH]c3ccccc23)nc(Oc2cccc(NC(=O)C=C)c2)n1

InChI Key InChIKey=LVURDXDDOIWLAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111473   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111473(CHEMBL3604937)
Affinity DataIC50: 17nMAssay Description:Inhibition of cSrc T338M/S345C mutant (unknown origin) pre-incubated for 30 mins before substrate and ATP addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111473(CHEMBL3604937)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in Sf9 cells pre-incubated for 30 mins before substrate and ATP addition by homogeneous time-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed