BDBM50111728 4-Fluoro-2-({1-[((R)-1-formyl-4-guanidino-butylcarbamoyl)-methyl]-6-methyl-2-oxo-1,2-dihydro-pyridin-3-ylsulfamoyl}-methyl)-benzoic acid methyl ester::CHEMBL19831

SMILES COC(=O)c1ccc(F)cc1CS(=O)(=O)Nc1ccc(C)n(CC(=O)N[C@H](CCCNC(N)=N)C(O)=O)c1=O

InChI Key InChIKey=OECPVFSZEWVKDZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111728   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111728(4-Fluoro-2-({1-[((R)-1-formyl-4-guanidino-butylcar...)
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111728(4-Fluoro-2-({1-[((R)-1-formyl-4-guanidino-butylcar...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111728(4-Fluoro-2-({1-[((R)-1-formyl-4-guanidino-butylcar...)
Affinity DataKi:  1.81E+3nMAssay Description:In vitro inhibitory constant against factor Xa (FXa) was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed