BDBM50111741 CHEMBL19666::N-(5-Carbamimidoyl-thiophen-2-ylmethyl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide

SMILES Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccc(s1)C(N)=N

InChI Key InChIKey=MHZINYCTUDNOIC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111741   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111741(N-(5-Carbamimidoyl-thiophen-2-ylmethyl)-2-(6-methy...)
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111741(N-(5-Carbamimidoyl-thiophen-2-ylmethyl)-2-(6-methy...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111741(N-(5-Carbamimidoyl-thiophen-2-ylmethyl)-2-(6-methy...)
Affinity DataKi:  96nMAssay Description:In vitro inhibitory constant against factor Xa (FXa) was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed