BDBM50112274 Acetic acid 9-naphthalen-2-ylmethylene-7-aza-tricyclo[4.3.1.0*3,7*]dec-2-ylmethyl ester::CHEMBL58253

SMILES CC(=O)OCC1C2CCC3CC1\C(CN23)=C\c1ccc2ccccc2c1

InChI Key InChIKey=AUASRRWSKHUBGZ-YBFXNURJSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112274   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112274(Acetic acid 9-naphthalen-2-ylmethylene-7-aza-tricy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of high affinity re-uptake of [3H]5-HT (serotonin) into nerve ending synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112274(Acetic acid 9-naphthalen-2-ylmethylene-7-aza-tricy...)
Affinity DataKi:  652nMAssay Description:Ability to inhibit high affinity reuptake of [3H]DA from dopamine transporter into nerve endings synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112274(Acetic acid 9-naphthalen-2-ylmethylene-7-aza-tricy...)
Affinity DataKi:  672nMAssay Description:Ability to inhibit high affinity reuptake of [3H]-NE (Norepinephrine transporter) into nerve ending synaptosomes prepared from brain regionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed