BDBM50112297 Benzoic acid 9-(4-bromo-3-chloro-benzylidene)-7-aza-tricyclo[4.3.1.0*3,7*]dec-2-ylmethyl ester::CHEMBL301020

SMILES Clc1cc(\C=C2/CN3C4CCC3C(COC(=O)c3ccccc3)C2C4)ccc1Br

InChI Key InChIKey=QBNBCBDYUDSSDZ-LICLKQGHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112297   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112297(Benzoic acid 9-(4-bromo-3-chloro-benzylidene)-7-az...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of high affinity re-uptake of [3H]5-HT (serotonin) into nerve ending synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112297(Benzoic acid 9-(4-bromo-3-chloro-benzylidene)-7-az...)
Affinity DataKi:  3.84E+3nMAssay Description:Ability to inhibit high affinity reuptake of [3H]-NE (Norepinephrine transporter) into nerve ending synaptosomes prepared from brain regionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112297(Benzoic acid 9-(4-bromo-3-chloro-benzylidene)-7-az...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit high affinity reuptake of [3H]DA from dopamine transporter into nerve endings synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed