BDBM50112356 CHEMBL3609373
SMILES OS(=O)(=O)C(C(=O)Nc1ccc(NC(=O)C(=O)Nc2ccc(I)cc2)cc1)c1ccccc1
InChI Key InChIKey=WYXKKFORWNIOFC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50112356
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Competitive inhibition of phosphatase activity of SHP2 (unknown origin) using pNPP as a substrate Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human LMWPTP using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase CDC14A(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human VHR using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human LAR using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase mu(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPmu using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase gamma(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPgamma using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of phosphatase activity of SHP2 (unknown origin) using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPbeta using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPalpha using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human HePTP using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human LYP using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of phosphatase activity of human PTP1B using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of phosphatase activity of human SHP1 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 5(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPepsilon using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair