BDBM50113889 3-[3,5-Difluoro-6-(3-methoxy-phenoxy)-4-methyl-pyridin-2-yloxy]-benzamidine::CHEMBL310575

SMILES COc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1

InChI Key InChIKey=JEKZQUJYJLAANC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113889   

TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113889(3-[3,5-Difluoro-6-(3-methoxy-phenoxy)-4-methyl-pyr...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113889(3-[3,5-Difluoro-6-(3-methoxy-phenoxy)-4-methyl-pyr...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113889(3-[3,5-Difluoro-6-(3-methoxy-phenoxy)-4-methyl-pyr...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed