BDBM50114282 (S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-phenyl}-2-(5-nitro-pyridin-2-ylamino)-propionic acid::CHEMBL38497

SMILES OC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)Nc1ccc(cn1)[N+]([O-])=O

InChI Key InChIKey=GEUAZGDNCFIZMN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114282   

TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114282((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50: 260nMAssay Description:Inhibition of very late antigen 4 from HL60 lysate in a protein-based ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114282((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50: 260nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114282((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of very late antigen 4 expressed in Jurkat cell line, in a cell-based adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114282((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed