BDBM50114726 CHEMBL94745::N-[2-(5-Methoxy-2-pyridin-3-ylmethyl-benzofuran-3-yl)-ethyl]-acetamide

SMILES COc1ccc2oc(Cc3cccnc3)c(CCNC(C)=O)c2c1

InChI Key InChIKey=GGESSWUOGJXGCX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114726   

TargetMelatonin receptor type 1B(Human)
University of Urbino Carlo Bo

Curated by ChEMBL
LigandPNGBDBM50114726(N-[2-(5-Methoxy-2-pyridin-3-ylmethyl-benzofuran-3-...)
Affinity DataKi:  3.5nMAssay Description:Displacement of 2-[125I]iodoMLT from human MT2 receptor stably expressed in HEK cells incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMelatonin receptor type 1B(Human)
University of Urbino Carlo Bo

Curated by ChEMBL
LigandPNGBDBM50114726(N-[2-(5-Methoxy-2-pyridin-3-ylmethyl-benzofuran-3-...)
Affinity DataKi:  3.53nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]iodomelatonin as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114726(N-[2-(5-Methoxy-2-pyridin-3-ylmethyl-benzofuran-3-...)
Affinity DataKi:  29nMAssay Description:Binding affinity on human melatonin receptor type 1A stably transfected in human embryonic kidney (HEK 293) using 2-[125I]iodomelatonin as radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114726(N-[2-(5-Methoxy-2-pyridin-3-ylmethyl-benzofuran-3-...)
Affinity DataKi:  29nMAssay Description:Displacement of 2-[125I]iodoMLT from human MT1 receptor stably expressed in HEK cells incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed