BDBM50115010 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-phenyl)-urea::CHEMBL42948

SMILES O=C(NCCCN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N

InChI Key InChIKey=DFMMVTOIQOKHSC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115010   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115010(1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-...)
Affinity DataIC50: 200nMAssay Description:In vitro C-C chemokine receptor type 3 activity of compound by using eotaxin induced human eosinophil chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115010(1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]eotaxin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115010(1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-...)
Affinity DataKi:  770nMAssay Description:Inhibition of [125I]-eotaxin binding to serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed