BDBM50115031 1-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-propyl}-3-(3-cyano-phenyl)-urea::CHEMBL48873

SMILES Clc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1

InChI Key InChIKey=QPYSQIOCOXFUJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115031   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115031(1-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-propyl}-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115031(1-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-propyl}-...)
Affinity DataIC50: 200nMAssay Description:In vitro C-C chemokine receptor type 3 activity of compound by using eotaxin induced human eosinophil chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed